promoter-proximal element

Objective: To identify the transcriptional regulation element in the promoter region of HBD 2 gene.

目的：对在LPS、TNFα刺激下，人β防御素2基因5′端转录调控机制进行初步分析。

Ets-1 interacted selectively with the~-1350GGAA~-1347 Ets element in the P21WAF1/ CIP1 promoter. Mutation of this element reduced basal and Ets-1-inducible P21WAF1/ CIP1 promoter-dependent expression.

Ets-1选择性地作用于P21WAF1/CIP1启动子中-1350GGAA-1347Ets元件，该元件的序列突变可降低基础表达和Ets-1诱导的P21WAF1/CIP1启动子依赖的表达。

The serum-responsive element in the PCNA 5 ′ promoter, the transcriptional regulation of PCNA gene in the cell cycle DNA damage checkpoint, were elucidated in detail.

538~+60区域启动子的调控做了比较全面的分析，着重研究了5′启动子中的血清刺激应答元件以及PCNA在细胞周期DNA损伤检查点（checkpoint）机制中的转录调控。

Objective To investigate if a bacterial enhancer-like element ( BELE) in the upstream region of Escherichia coli gln Ap2 gene had strict promoter selectivity.

目的探讨大肠杆菌谷氨酰胺合成酶基因上游增强子样序列（BELE）有无严格的启动子选择性。

GC-box is not a key cis-acting element in human insulin gene promoter

GC盒不是人胰岛素基因启动子中关键顺式作用元件